2 products were found matching "1799633-27-4"!
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S63845
Item number: TGM-T5346-10mg
Description: S63845 is a selective MCL-1 inhibitor(Kd: 0.19 nM). Target: BCL. Smiles: CN1CCN(CCOc2ccc(-c3c(sc4ncnc(O[C@@H](Cc5ccccc5OCc5ccnn5CC(F)(F)F)C(O)=O)c34)-c3ccc(F)o3)c(C)c2Cl)CC1. References: András Kotschy, Zoltán Szlavik, James Murray.The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer...
| Application: | Mcl-1 inhibitor |
| CAS | 1799633-27-4 |
| MW: | 829.26 D |
From 79.00€
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S63845
Item number: Cay21131-5
S63845 is an inhibitor of myeloid cell leukemia 1 (Mcl-1, Ki = 0.19 nM), a pro-survival protein that is overexpressed in many cancers. It induces cell death in multiple myeloma, leukemia, and lymphoma cell lines (IC50s = via mitochondrial apoptosis. S63845 acts synergistically with trametinib (Cay-16292), lapatinib...
| Keywords: | alpha(R)-[[(5S)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(5-fluoro-2-furanyl)thieno[2,3-d]pyrimi... |
| Application: | Mcl-1 inhibitor |
| CAS | 1799633-27-4 |
| MW: | 829.3 D |
From 117.00€
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