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Item number: TGM-T35528-2mg

Description: TD52 is an orally active inhibitor of cancerous inhibitor of PP2A (CIP2A). TD52 is an Erlotinib derivative and indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. Target: Akt, Apoptosis, Phosphatase. Smiles: C#Cc1cccc(Nc2nc3ccccc3nc2Nc2cccc(c2)C#C)c1. References: Chun-Yu Liu, et...

CAS	1798328-24-1
MW:	360.41 D

83.00€ *

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TD52

Item number: Cay37744-10

TD52 is a derivative of the EGFR tyrosine kinase inhibitor erlotinib (Cay-10483, Cay-35517). It decreases the viability of HA22T, Hep3B, PLC/PRF/5, and SK-HEP-1 hepatocellular carcinoma cells (IC50s = 0.9, 0.9, 0.8, and 1.2 µM, respectively). TD52 induces apoptosis in a variety of cancer cells, including HA22T and...

Keywords:	N2,N3-bis(3-ethynylphenyl)-2,3-quinoxalinediamine
Application:	Erlotinib derivative
CAS	1798328-24-1
MW:	360.4 D

From 128.00€ *

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