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Item number: Cay23417-10

PD 151746 is an inhibitor of calpain 1/µ-calpain (Ki = 0.26 µM). It is 20-fold selective for calpain 1 over calpain 2/m-calpain (Ki = 5.33 µM). It is also selective over cathepsin B, papain, trypsin, and thermolysin, (Kis = >200, >500, >500, and >500 µM, respectively) and does not inhibit basal calcineurin activity...

Keywords:	3-(5-fluoro-1H-indol-3-yl)-2-mercapto-2-propenoic acid
Application:	Calpain-1 inhibitor
CAS	179461-52-0
MW:	237.2 D

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