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Z-Leu-Leu-Leu-B(OH)2 [MG-262]
Z-Leu-Leu-Leu-B(OH)2 [MG-262]

Item number: AG-CP3-0024-C200

Solid lyophilized powder. Soluble in DMSO. Highly potent and selective cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome, Calpain and cathepsin inhibitor, Autophagy activator, Similar structure as MG-132 (AG-CP3-0011) but much higher...
Keywords: Z-LLL-B(OH)2, Proteasome Inhibitor III
Application: Proteasome inhibitor
CAS 179324-22-2
MW: 491,4 D
From 77.00€ *
Review
Z-Leu-Leu-Leu-B(OH)2
Z-Leu-Leu-Leu-B(OH)2

Item number: Cay10008311-1

Z-Leu-Leu-Leu-B(OH)2 is a proteasome inhibitor with diverse biological activities. It inhibits LPS-induced expression of FMS-related tyrosine kinase 1 (FLT1) in isolated human microvascular endothelial cells and macrophages. Z-Leu-Leu-Leu-B(OH)2 (1 µM) reduces heat shock-induced increases in heat shock protein 70...
Keywords: MG 262, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1R)-1-borono-3-methylbutyl]-L-leucinamide
Application: Proteasome inhibitor
CAS 179324-22-2
MW: 491.4 D
From 458.00€ *
Review
MG-262
MG-262

Item number: TGM-T21968-1mg

Description: MG-262 is a reversible proteasome inhibitor with multiple biological activities (MGCD-162, Mills 2004) (Morrison et al., 2005, Li et al., 2006) (Tang et al., 2006, Zhang et al., 2007). Target: Others. Smiles: [C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(C)C)=O)(C(N[C@@H](CC(C)C)B(O)O)=O)CC(C)C
CAS 179324-22-2
MW: 491.43 D
From 708.00€ *
Review