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KOTX1
KOTX1

Item number: Cay42249-1

An ALDH1A3 inhibitor (IC50 = 5.14 nM), potentiates glucose-induced insulin secretion from pancreatic islets isolated from patients with type 2 diabetes at 10 µM, decreases plasma insulin levels and reduces blood glucose levels in an IPGTT in diabetic db/db male mice at 40 mg/kg per day, decreases blood glucose...
Keywords: 3-ethyl-N-(7-fluoro-1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)-4-pyridinecarboxamide
Application: ALDH1A3 inhibitor
CAS 1788963-83-6
MW: 313.3 D
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