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Item number: Cay44962-10

Remibrutinib is a covalent inhibitor of Bruton's tyrosine kinase (BTK. IC50 = 1. nM). It selectively binds to BTK over bone marrow tyrosine kinase on chromosome X (BMX) and Tec (Kds = 0. 540, and 110 nM, respectively), as well as IL-2-inducible T cell kinase (Itk), EGFR, HER2, HER4, and JAK3 (Kds = >10,000 nM for...

Keywords:	LOU064,...
Application:	BTK inhibitor
CAS	1787294-07-8
MW:	507.54 D

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Remibrutinib

Item number: TGM-T16730-100mg

Description: Remibrutinib inhibits BTK activity with an IC50 value of 0.023 µM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment. Target: BTK. Smiles:...

Application:	Targets Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (BTK)
CAS	1787294-07-8
MW:	507.53 D

From 93.00€ *

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