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TA-01
TA-01

Item number: Cay24667-5

TA-01 is a derivative of the p38 MAPK inhibitor SB 203580 (Cay-13067, Cay-13344) and an inducer of cardiomyocyte differentiation. It is cardiomyogenic at concentrations less than 5 µM, increasing expression of the cardiomyocyte marker NKX2-5 by 2.2-fold and decreasing expression of mesoderm markers and the...
Keywords: 4-[2-(2,6-difluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-pyridine
Application: CK1epsilon / CK1Delta inhibitor
CAS 1784751-18-3
MW: 351.3 D
From 51.00€ *
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TA-01
TA-01

Item number: TGM-T4645-100mg

Description: TA-01 is a potent inhibitor of CK1 and p38 MAPK, with IC50 values of 6.4 nM for CK1epsilon, 6.8 nM for CK1delta, and 6.7 nM for p38 MAPK. Target: Casein Kinase, p38 MAPK, Autophagy. Smiles: Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1c(F)cccc1F. References: Laco F, et al. Cardiomyocyte differentiation of...
Application: CK1epsilon / CK1Delta inhibitor
CAS 1784751-18-3
MW: 351.32 D
From 30.00€ *
Review