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Item number: Cay21885-1

Chemokine (C-C motif) receptor 4 (CCR4) antagonist is an antagonist of CCR4. It inhibits activation of CCR4 by chemokine (C-C motif) ligand 22 (CCL22) in a [35S]GTPgammaS assay and also inhibits chemotaxis in human and mouse CCR4-expressing B300-19 cells (IC50s = 18, 140, and 39 nM, respectively). CCR4 antagonist...

Keywords:	2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine, dihydrochloride
Application:	C-C chemokine receptor type 4 antagonist
CAS	1784252-84-1
MW:	540.6 D

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