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Item number: Cay46259-10

Revaprazan is a potassium-competitive acid blocker (P-CAB) that inhibits H+/K+-ATPase activity in porcine gastric mucosa membrane vesicles (IC50 = 0.35 µM). It rescues H. pylori-induced cytotoxicity and H. pylori-induced increases in prostaglandin E2 (PGE2, Cay-14010) levels in AGS gastric epithelial cells, and it...

Keywords:	SB-641257, YH 1885, 4-(3,4-dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4- fluorophenyl)-5,6-dimethyl-2-pyrimidinamine,...
Application:	Potassium-competitive acid blocker
CAS	178307-42-1
MW:	398.91 D

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Revaprazan hydrochloride

Item number: TGM-T2405-100mg

Description: Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. Target: ATPase, COX, Antibacterial. Smiles: Cl.CC1N(CCc2ccccc12)c1nc(Nc2ccc(F)cc2)nc(C)c1C. References: Lee JS, et al.J Clin Biochem Nutr. 2012...

Keywords:	YH1885
CAS	178307-42-1
MW:	398.9 D

From 36.00€ *

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