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Cudetaxestat
Item number: TGM-T63190-100mg
Description: Cudetaxestat (BLD-0409) is a potent, orally active autotaxin inhibitor. Target: PDE. Smiles: CCCn1cc(cn1)-n1c(Cl)c(Sc2cccc(C(O)=O)c2F)c2ccc(Cl)c(F)c12. References: Tan Z, et al. An updated patent review of autotaxin inhibitors (2017-present). Expert Opin Ther Pat. 2021,31(5):421-434.
| Keywords: | BLD-0409 |
| Application: | Autotaxin (ENPP2) inhibitor |
| CAS | 1782070-21-6 |
| MW: | 482.33 D |
From 71.00€
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Cudetaxestat
Item number: Cay38789-1
Cudetaxestat is an inhibitor of autotaxin (IC50 = =0.5 µM), also known as ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2). It reduces migration of MDA-MB-435 melanoma cells (IC50 = 15 nM). Cudetaxestat reduces blood glucose levels in a glucose tolerance test, as well as baseline blood...
| Keywords: | 3-[[2,6-dichloro-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl]thio]-2-fluoro-benzoic acid |
| Application: | Autotaxin (ENPP2) inhibitor |
| CAS | 1782070-21-6 |
| MW: | 482.3 D |
From 111.00€
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