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Item number: Cay28454-10

ZK 756326 is a non-peptide agonist of the CC chemokine receptor CCR8. It inhibits binding of CCL1 to human CCR8 (IC50 = 1.8 µM) and induces Gai-mediated calcium-mobilization in U87 cells expressing the receptor. It exhibits greater than 28-fold selectivity for CCR8 over 26 other GPCRs but also binds to the serotonin...

Keywords:	2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]-ethanol, dihydrochloride
Application:	CCR8 agonist
CAS	1780259-94-0
MW:	429.4 D

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