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Item number: TGM-T13918-100mg

Description: Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the sensitivity to the activation of extracellular Ca2+. Target: CaSR. Smiles: Cl.COc1cccc(c1)[C@@H](C)NCCCc1ccccc1Cl. References: Wada, M., et al....

Keywords:	R-568 hydrochloride, R-568 (hydrochloride)
Application:	Targets calcium-sensing receptor (CASR)
CAS	177172-49-5
MW:	340.29 D

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R-568

Item number: Cay17415-10

R-568 is a calcimimetic and positive allosteric modulator of the calcium-sensing receptor (CaSR). It potentiates extracellular calcium-induced increases in intracellular calcium release and inhibits the secretion of parathyroid hormone (PTH, IC50 = 27 nM) in bovine parathyroid cells. R-568 decreases PTH and plasma...

Keywords:	KRN 568, NPS R-568, Tecalcet, 2-chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine, monohydrochloride
Application:	Allosteric CaSR activator, calcimimetic
CAS	177172-49-5
MW:	340.3 D

From 52.00€ *

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