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Ambrisentan
Ambrisentan

Item number: TGM-T1655-10mg

Description: Ambrisentan (BSF 208075) is an endothelin receptor antagonist used in the therapy of pulmonary arterial hypertension (PAH). Ambrisentan has been associated with a low rate of serum enzyme elevations during therapy but has yet to be implicated in cases of clinically apparent acute liver injury. Target:...
Keywords: BSF 208075, BSF-208075, LU 208075
Application: Targets endothelin receptor type A (EDNRA)
CAS 177036-94-1
MW: 378.42 D
From 31.00€ *
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Ambrisentan
Ambrisentan

Item number: Cay23669-5

Ambrisentan is a nonpeptide endothelin A (ETA) receptor antagonist (IC50s = 0.251, 0.316, 0.398, 251, and 630 nM for rat preparations of heart, bladder, kidney, lung, and cerebral cortex, respectively). It inhibits contraction of isolated rabbit aortic rings induced by endothelin-1 (ET-1, Cay-24127) by 43.23% when...
Keywords: alphaS-[(4,6-dimethyl-2-pyrimidinyl)oxy]-beta-methoxy-beta-phenyl-benzenepropanoic acid
Application: Endothelin A (ETA) receptor antagonist
CAS 177036-94-1
MW: 378.4 D
From 44.00€ *
Review