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Item number: Cay21180-1

Bisindolylmaleimide I (BIM I) is a highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM) that is structurally similar to the poorly selective PKC inhibitor staurosporine (Cay-81590). It acts as a competitive inhibitor for the ATP binding site of PKC and shows high selectivity for PKCalpha,...

Keywords:	BIM I, GF109203X, Gö 6850, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione,...
Application:	PKC inhibitor
CAS	176504-36-2
MW:	449 D

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Bisindolylmaleimide XI-Hydrochloride

Item number: AG-CR1-0110-M001

Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki= 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Inhibits necrosis. Blocks hERG...

Keywords:	GF 109203X, Gö 6850, BIM I
Application:	PKC inhibitor
CAS	176504-36-2

From 66.00€ *

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