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Item number: TGM-T16849-100mg

Description: SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM). Target: Neurokinin receptor. Smiles: Nc1cccc(CN2C(Cc3ccccc3)C(O)C(O)C(Cc3ccccc3)N(Cc3cccc(N)c3)C2=O)c1. References: Sarau HM, et al. Nonpeptide tachykinin receptor antagonists. II. Pharmacological and...

Application:	NK3 receptor antagonist
CAS	174635-69-9
MW:	380.48 D

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SB 222200

Item number: Cay29422-10

SB 222200 is a neurokinin-3 (NK3) receptor antagonist (IC50 = 18.4 nM). It is selective for NK3 over NK1 and NK2 receptors (IC50s = 250 and >100,000 nM, respectively). SB 222200 decreases calcium mobilization induced by neurokinin B (Cay-24542) with an IC50 value of 265 nM in HEK293 cells expressing the recombinant...

Keywords:	3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide
Application:	NK3 receptor antagonist
CAS	174635-69-9
MW:	380.5 D

From 161.00€ *

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