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Item number: Cay38392-1

2,3,7,8-Tetrachlorodibenzo-p-dioxin is a toxicant and an agonist of the aryl hydrocarbon receptor (AhR, ED50 = 0.2 nmol/kg in a reporter assay using chicken embryos). It also induces AhR ubiquitination and degradation in Hepa-1c1c7 hepatic cells when used at a concentration of 1 nM. Oral administration of...

Keywords:	2,3,7,8-Tetrachlorodibenzo-1,4-dioxin, 2,3,7,8-Tetrachlorodibenzodioxin, TCDBD, TCDD,...
Application:	AhR agonist, toxicant
CAS	1746-01-6
MW:	322 D

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