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TBB
Item number: Cay14453-10
TBB is an ATP/GTP-competitive inhibitor of casein kinase 2 (CK2, IC50 = 0.15 µM for rat liver CK2). It also inhibits PIM3 and DYRK2 with IC50 values of 0.86 and 0.99 µM, respectively, and several other protein kinases with IC50 values in the low micromolar range but displays less than 10% inhibition at 26 additional...
| Keywords: | NSC 231634, Tetrabromobenzotriazole, 4,5,6,7-tetrabromo-1H-benzotriazole |
| Application: | Casein kinase 2 inhibitor |
| CAS | 17374-26-4 |
| MW: | 434.7 D |
From 59.00€
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TBB
Item number: AG-CR1-3660-M005
Solid. Soluble in DMSO (20mg/ml). ATP/GTP-competitive cell permeable casein kinase II (CK2) inhibitor (IC50=0.9µM for rat liver. Less potently inhibits CCK2/cyclin A, GSK3beta and phosphorylase kinase (IC50=15.6, 11.2 and 8.7µM, respectively). Binds to the Val66 residue of CK2 and inhibits the binding of ATP/GTP,...
| Keywords: | 4,5,6,7-Tetrabromo-2-azabenzimidazole, Tetrabromobenzotriazole, NSC 231634, TBBt |
| Application: | ATP/GTP-competitive cell permeable casein kinase II (CK2) inhibitor |
| CAS | 17374-26-4 |
| MW: | 434,7 D |
From 44.00€
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TBB
Item number: TGM-T2695-100mg
Description: TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2). Target: CDK, GSK-3, Casein Kinase. Smiles: BrC1=C2C(=C(Br)C(Br)=C1Br)N=NN2. References: De Moliner E, et al. Alternative binding modes of an inhibitor to two different kinases. Eur J Biochem....
| Keywords: | Casein Kinase II Inhibitor I, 4,5,6,7-tetrabromobenzotriazole, NSC 231634 |
| CAS | 17374-26-4 |
| MW: | 434.71 D |
From 29.00€
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