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Aliskiren (hemifumarate)
Item number: Cay19640-10
Aliskiren is a nonpeptide inhibitor of renin (IC50 = 0.6 nM for the human enzyme). Aliskiren (10 and 30 mg/kg per day) reduces blood pressure and prevents albuminuria in renin-overexpressing TG(mRen-2)27 rats in a model of streptozotocin-induced diabetes. It also reduces cardiac hypertrophy and fibrosis induced by...
| Keywords: | CGP 60536, SPP 100,... |
| Application: | Renin inhibitor |
| CAS | 173334-58-2 |
| MW: | 609.8 D |
From 49.00€
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Aliskiren hemifumarate
Item number: LKT-A4534.100
Aliskiren is a highly potent and selective inhibitor of human renin, which catalyses the rate-limiting step of the renin-angiotensin system. Aliskiren may also have neuroprotective action against Abeta toxicity.
| Keywords: | (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methy... |
| CAS | 173334-58-2 |
| MW: | 609.83 D |
From 128.00€
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Aliskiren hemifumarate
Item number: TGM-T1520-100mg
Description: Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity. Target: RAAS, Autophagy. Smiles:...
| Keywords: | SPP 100, CGP60536B, CGP 60536 |
| Application: | Targets renin [EC:3.4.23.15] (REN) |
| CAS | 173334-58-2 |
| MW: | 1219.6 D |
From 33.00€
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