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Item number: Cay21916-10

2-(Phosphonomethyl)-pentanedioic acid (2-PMPA) is a potent inhibitor of glutamate carboxypeptidase II (GCP II), also known as N-acetylated alpha-linked dipeptidase (NAALADase), with a Ki value of 98 pM for release of glutamate from the NAALADase peptide substrate N-acetylasparatylglutamate (NAAG). It is selective...

Keywords:	2-PMPA, 2-(phosphonomethyl)-pentanedioic acid
CAS	173039-10-6
MW:	226.1 D

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2-PMPA

Item number: TGM-T3440-100mg

Description: 2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM). Target: Carboxypeptidase. Smiles: C(CCC(O)=O)(CP(=O)(O)O)C(O)=O. References: Rais R, et al. Bioanalytical method for evaluating the pharmacokinetics of the GCP-II...

Keywords:	2-(Phosphonomethyl)pentanedioic acid
CAS	173039-10-6
MW:	226.12 D

From 57.00€ *

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