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Tadalafil
Tadalafil

Item number: TGM-T1398-10mg

Description: Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity that selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase (PDE-5), preventing cGMP degradation in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis, thereby...
Keywords: Cialis, IC-351
Application: Targets cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35] (PDE5)
CAS 171596-29-5
MW: 389.4 D
From 33.00€ *
Review
Tadalafil
Tadalafil

Item number: Cay14024-10

Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5, IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 µM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-alpha, IL-1beta, and IL-6 and...
Keywords: (6R)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12aR-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Application: Phosphodiesterase (PDE) V inhibitor
CAS 171596-29-5
MW: 389.4 D
From 61.00€ *
Review
Tadalafil (CRM)
Tadalafil (CRM)

Item number: Cay41133-1

Tadalafil (CRM) (Cay-41133) is a certified reference material categorized as a phosphodiesterase 5 (PDE5) inhibitor. Tadalafil has been found in samples seized by law enforcement. This product is intended for analytical forensic applications. This product is also available as a general research tool...
Keywords: (6R)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12aR-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Application: Certified reference material, PDE5 inhibitor
CAS 171596-29-5
MW: 389.4 D
226.00€ *
Review
Tadalafil
Tadalafil

Item number: CDX-T0455-M050

White to beige powder. Soluble in DMSO (20mg/ml) or DMF (25mg/ml). Chemical. CAS: 171596-29-5. Formula: C22H19N3O4. MW: 389.40. Tadalafil is a potent long-acting and selective inhibitor of the cGMP specific phosphodiesterase 5 (PDE5, IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 µM),...
Keywords: GF196960, (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1,2:1,6]pyrido[3,4-b]indole-1,4-dione
CAS 171596-29-5
MW: 389,40 D
From 85.00€ *
Review