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Exatecan
Item number: BPS-84321-1
Exatecan, also known as DX-8951, is a DNA topoisomerase I inhibitor. ADC (antibody drug conjugates) are a promising therapeutic strategy. ADCs are composed of an antibody that can bind to a target in the cells, such as HER3 (human epidermal growth factor receptor 3), a linker and a payload (cytotoxic drug)....
| Application: | ADC preparation, in vitro inhibition studies |
| CAS | 171335-80-1 |
| MW: | 435.45 |
From 270.00€
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Exatecan
Item number: TGM-T11249-100mg
Description: Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 µM (0.975 µg/mL).Exatecan has antitumor activity and may be used in cancer research. Target: Topoisomerase, ADC Cytotoxin. Smiles: N[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6....
| Keywords: | DX-8951, DX-8951f |
| CAS | 171335-80-1 |
| MW: | 435.45 D |
From 29.00€
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