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Item number: Cay21408-5

(R,S)-CHPG is a potent and selective agonist at metabotropic glutamate receptor 5 (mGluR5). In CHO cells, it had an EC50 of 750 µM for calcium mobilization in mGluR5a-expressing cells but was inactive in mGluR1a-expressing cells. In transfected HEK293 cells, (R,S)-CHPG bound mGluR1a and mGluR5a (Kis = 0.9 and 3.9...

Keywords:	Chlorohydroxyphenylglycine, CHPG, alpha-amino-2-chloro-5-hydroxy-benzeneacetic acid
Application:	mGluR5 agonist
CAS	170846-74-9
MW:	201.6 D

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