2 products were found matching "1708113-43-2"!

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Item number: Cay30505-1

An HDAC6 inhibitor (IC50 = 3 nM), increases the levels of acetylated alpha-tubulin in SK-N-BE(2) cells in a concentration-dependent manner, prevents cisplatin-induced decreases in mitochondrial OCR and mitochondrial motility in tibial nerves isolated from mice at 10 mg/kg per day, inhibits cisplatin-induced...

Keywords:	2-[(4,4-difluoro-1-phenylcyclohexyl)amino]-N-hydroxy-5-pyrimidinecarboxamide
Application:	HDAC6 inhibitor
CAS	1708113-43-2
MW:	348.4 D

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ACY-1083

Item number: TGM-T10244-100mg

Description: ACY-1083 is a selective, brain-penetrating HDAC6 inhibitor (IC50: 3 nM) that effectively reverses chemotherapy-induced peripheral neuropathy. Target: HDAC. Smiles: ONC(=O)c1cnc(NC2(CCC(F)(F)CC2)c2ccccc2)nc1. References: Krukowski K, et al. HDAC6 inhibition effectively reverses chemotherapy-induced...

CAS	1708113-43-2
MW:	348.35 D

From 146.00€ *

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