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Item number: TGM-T36395-100mg

Description: Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors. Target: Epigenetic Reader Domain. Smiles: Cn1cc(-c2cc(ccc2OCC2CC2)S(C)(=O)=O)c2ccccc2c1=O. References: CELGENE QUANTICEL RESEARCH, INC. PROCESS FOR THE PREPARATIO NOFBROMODO MAININHIBI...

Keywords:	CC-90010
Application:	Targets bromodomain-containing protein 2 (BRD2)
CAS	1706738-98-8
MW:	383.46 D

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Trotabresib

Item number: Cay36292-1

Trotabresib is an inhibitor of bromodomain-containing protein 4 (BRD4, IC50 = =0.5 µM). It inhibits the proliferation of Raji Burkitt's lymphoma and HL-60 leukemia cells (IC50 = =0.5 µM for both).Formal Name: 4-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl]-2-methyl-1(2H)-isoquinolinone. CAS Number: 1706738-98-8....

Keywords:	BMS-986378, CC-90010, 4-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl]-2-methyl-1(2H)-isoquinolinone
Application:	BRD4 inhibitor
CAS	1706738-98-8
MW:	383.5 D

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