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Item number: Cay43952-1

AZ-PFKFB3-67 is an inhibitor of 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase 3 (PFKFB3, IC50 = 0.011 µM). It is selective for PFKFB3 over PFKFB1 and PFKFB2 (IC50s = 1.13 and 0.159 µM). It inhibits the formation of fructose-1,6-bisphosphate in A549 cells (IC50 = 0.281 µM). SMILES...

Keywords:	N-[4-[[3-cyano-1-[(3,5-dimethyl-4-isoxazolyl)methyl]-1H-indol-5-yl]oxy]phenyl]-2S-pyrrolidinecarboxamide
Application:	PFKFB3 inhibitor
CAS	1704741-11-6
MW:	455.52 D

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