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Item number: Cay22985-1

BLU-285 is a dual inhibitor of KIT receptor and platelet-derived growth factor receptor alpha (PDGFRalpha) tyrosine kinases with activating loop mutations (IC50s = 0.27 and 0.24 nM for KITD816V and PDGFRalphaD842V, respectively). It is >150-fold selective for KITD816V and PDGFRalphaD842V over a kinase panel at a...

Keywords:	Avapritinib,...
Application:	PDGFR alpha D842V / KIT Exon 17 mutant inhibitor
CAS	1703793-34-3
MW:	498.6 D

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