3 products were found matching "170364-57-5"!
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Enzastaurin
Item number: Cay11601-5
Enzastaurin is a potent inhibitor of PKCbeta (IC50 = 6 nM), with modest selectivity over PKCalpha, PKCgamma, and PKCepsilon (IC50 = 39, 83, and 110 nM, respectively). At 3 µM, enzastaurin also inhibits signaling through the Akt pathway. It suppresses angiogenesis, induces apoptosis, and reduces proliferation of...
| Keywords: | LY317615, 3-(1-methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione |
| Application: | PKCbeta inhibitor |
| CAS | 170364-57-5 |
| MW: | 515.6 D |
From 115.00€
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Enzastaurin, Free Base
Item number: E3317-75.10
Enzastaurin inhibits PKCb, PKCa, PKCy and PKCe with IC50's of 0.006, 0.039, 0.083 and 0.110uM, respectively. Enzastaurin apparently inhibits tumor growth via multiple mechanisms: suppression of tumor cell proliferation, induction of tumor cell apoptosis and inhibition of tumor-induced angiogenesis. Solubility:...
| CAS | 170364-57-5 |
| MW: | 515.60 |
248.00€
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Enzastaurin, Free Base (LY-317615, D04014, CAS...
Item number: LC-E-4506_100mg
Soluble in DMSO at 7.1 mg/mL with slight warming, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 1-10 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Keywords: | LY317615, 3-(1-methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione |
| Application: | PKCbeta inhibitor |
| CAS | 170364-57-5 |
| MW: | 515,6 D |
From 105.00€
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