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Nepicastat (hydrochloride)
Item number: Cay22126-1
Nepicastat is an inhibitor of dopamine beta-hydroxylase (DBH, IC50 = 9 nM for the purified human enzyme). It is selective for DBH over a panel of 12 enzymes and 13 neurotransmitter receptors (IC50s or Kis = >10 µM). Nepicastat dose-dependently reduces norepinephrine content and increases dopamine content in the...
| Keywords: | RS 25560-197, 5-(aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione,... |
| Application: | DBH inhibitor |
| CAS | 170151-24-3 |
| MW: | 331.8 D |
From 53.00€
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Nepicastat hydrochloride
Item number: TGM-T6604-100mg
Description: Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-beta-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicastat for twelve other enzymes and thirteen neurotransmitter receptors is negligible....
| Keywords: | Nepicastat (SYN-117) HCl, Nepicastat HCl, RS-25560-197 hydrochloride, SYN-117 hydrochloride |
| Application: | DBH inhibitor |
| CAS | 170151-24-3 |
| MW: | 331.81 D |
From 49.00€
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