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JH-II-127
JH-II-127

Item number: Cay22905-5

JH-II-127 is an orally bioavailable inhibitor of wild-type (WT) and mutant forms of leucine-rich repeat kinase 2 (LRRK2). It inhibits WT LRRK2, as well as LRRK2 containing the G2019S and A2016T substitution mutations (IC50s = 6.6, 2.2, and 47.7 nM, respectively), which are present in certain patients with...
Keywords: [4-[[5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone
Application: LRRK2 inhibitor
CAS 1700693-08-8
MW: 416.9 D
From 43.00€ *
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JH-II-127
JH-II-127

Item number: LKT-J291331.1

Keywords: Pyrrolopyrimidine
Application: LRRK2 inhibitor
CAS 1700693-08-8
MW: 416.87 D
From 81.00€ *
Review