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IPI-549
IPI-549

Item number: Cay26416-1

IPI-549 is an inhibitor of PI3Kgamma (IC50s = 16, 3,200, 3,500, and >8,400 nM for PI3Kgamma, PI3Kalpha, PI3Kbeta, and PI3Kdelta, respectively). It is greater than 100-fold selective for PI3Kgamma over a panel of 468 mutant and nonmutant protein and lipid kinases, including Class II PI3K isoforms, and a panel of 80 G...
Keywords: 2-amino-N-[(1S)-1-[1,2-dihydro-8-[2-(1-methyl-1H-pyrazol-4-yl)ethynyl]-1-oxo-2-phenyl-3-isoquinolinyl]ethyl]-pyrazolo[1,5-...
Application: PI3Kgamma inhibitor
CAS 1693758-51-8
MW: 528.6 D
From 54.00€ *
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IPI-549
IPI-549

Item number: LKT-I611325.100

Selective inhibitor of the gamma isoform of PI3K (PI3Kgamma).
Keywords: IPI 549, IPI549
Application: PI3Kgamma inhibitor
CAS 1693758-51-8
MW: 528.58 D
From 180.00€ *
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Eganelisib
Eganelisib

Item number: TGM-T5432-100mg

Description: Eganelisib (IPI-549) is an inhibitor of PI3Kgamma (IC50 = 16, 3,200, 3,500, and >8,400 nM for PI3Kgamma, PI3Kalpha, PI3Kbeta, and PI3Kdelta, respectively). Target: PI3K. Smiles: C[C@H](NC(=O)c1c(N)nn2cccnc12)c1cc2cccc(C#Cc3cnn(C)c3)c2c(=O)n1-c1ccccc1. References: De Vera AA1, Gupta P.et...
Keywords: IPI-549
Application: Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (PIK3CG)
CAS 1693758-51-8
MW: 528.56 D
From 39.00€ *
Review