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zanubrutinib
Item number: TGM-T7584-100mg
Description: Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK). Target: BTK. Smiles: NC(=O)c1c2NCC[C@@H](C3CCN(CC3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1. References: Li N , Sun Z , Liu Y , et al. Abstract 2597: BGB-3111 is a novel and highly selective Bruton's tyrosine kinase (BTK) inhibitor[J]....
| Keywords: | BGB-3111 |
| Application: | Targets Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (BTK) |
| CAS | 1691249-45-2 |
| MW: | 471.55 D |
From 57.00€
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Zanubrutinib
Item number: Cay28924-1
Zanubrutinib is a potent and covalent inhibitor of Bruton's tyrosine kinase (BTK, IC50 = 0.3 nM). It is selective for BTK over a panel of 304 kinases at 1 µM but does inhibit EGFR, Tec, Blk, BMX, HER4, and TXK (IC50s = 0.62-33 nM). Zanubrutinib inhibits phosphorylation of BTK at Y233 (IC50 = 1.8 nM) in Ramos cells...
| Keywords: | BGB-3111,... |
| Application: | Potent covalent BTK (Bruton's tyrosine kinase ) inhibitor |
| CAS | 1691249-45-2 |
| MW: | 471.6 D |
From 85.00€
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