2 products were found matching "1690172-25-8"!
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I-191
Item number: TGM-T7137-100mg
Description: I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells. Target: Protease-activated Receptor. Smiles: CC(C)(C)c1cc(nn2cc(nc12)C(=O)N1CCNC(=O)C1(C)C)-c1ccc(F)cc1. References: Jiang Y , Yau M K , Lim J , et al. A potent antagonist...
| Application: | PAR2 antagonist |
| CAS | 1690172-25-8 |
| MW: | 423.48 D |
From 81.00€
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I-191
Item number: Cay37553-100
I-191 is an antagonist of proteinase-activated receptor 2 (PAR2, IC50 = 72.4 nM in HT-29 cells expressing the human receptor). It inhibits trypsin-induced calcium release in HT-29 cells (IC50 = 200 nM for the human receptor). I-191 (0.1, 1, and 10 µM) reduces the migration of HT-29 cells in a scratch assay. It...
| Keywords: | 4-[[8-(1,1-dimethylethyl)-6-(4-fluorophenyl)imidazo[1,2-b]pyridazin-2-yl]carbonyl]-3,3-dimethyl-2-piperazinone |
| Application: | PAR2 antagonist |
| CAS | 1690172-25-8 |
| MW: | 423.5 D |
From 208.00€
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