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OSMI-1
Item number: TGM-T16409-100mg
Description: OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 µM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans. Target: Acyltransferase, Others. Smiles:...
| Application: | OGT inhibitor |
| CAS | 1681056-61-0 |
| MW: | 563.64 D |
From 34.00€
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OSMI-1
Item number: Cay21894-1
OSMI-1 is a quinolinone-6-sulfonamide that inhibits O-GlcNAc transferase (OGT, IC50 = 2.7 µM) in vitro. It is cell permeable and inhibits global O-GlcNAcylation in a dose-dependent manner in CHO cells. OSMI-1 induces a mass shift of nucleoporin62 (Nup62) that corresponds to the loss of O-GlcNAc residues and...
| Keywords: | alphaR-[[(1,2-dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-benzeneacetamide |
| Application: | OGT inhibitor |
| CAS | 1681056-61-0 |
| MW: | 563.6 D |
From 44.00€
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