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NXY-059
NXY-059

Item number: Cay22109-10

NXY-059 is a nitrone free radical spin trap with neuroprotective properties. It inhibits transport of tissue plasminogen activator (tPA) from the luminal to the abluminal compartment in an in vitro model of the blood-brain barrier (BBB) under ischemic conditions at a concentration of 250 µM. NXY-059 (10 mg/kg per h)...
Keywords: CPI-22, Disufenton Sodium, 4-[[(1,1-dimethylethyl)oxidoimino]methyl]-1,3-benzenedisulfonic acid, disodium salt
Application: Free radical trapping agent, neuroprotectant
CAS 168021-79-2
MW: 381.3 D
From 72.00€ *
Review
Disufenton sodium
Disufenton sodium

Item number: TGM-T6201-100mg

Description: Disufenton sodium (NXY-059), a new-type nitrone, exhibits potently neuroprotective effects. Target: Reactive Oxygen Species. Smiles: [Na+].[Na+].CC(C)(C)[N+](\[O-])=C\c1ccc(cc1S([O-])(=O)=O)S([O-])(=O)=O. References: Kuroda S, et al, J Cereb Blood Flow Metab, 1999, 19(7), 778-787.
Keywords: NXY059, Cerovive, NXY 059, NXY-059, OKN007
Application: Neuroprotectant, Free radical scavenger
CAS 168021-79-2
MW: 381.33 D
From 36.00€ *
Review