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Item number: Cay43994-10

JZP 361 is an inhibitor of monoacylglycerol lipase (MAGL, IC50 = 46 nM). It is selective for MAGL over fatty acid amide hydrolase (FAAH) and alpha/beta-hydrolase domain-containing protein 6 (ABHD6, IC50s = 7,240 and 1,790 nM, respectively). JZP 361 also antagonizes histamine activity in isolated guinea pig ileum...

Keywords:	[4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-1H-1,2,4-triazol-1-yl-methanone
Application:	Monoglyceride lipase inhibitor
CAS	1680193-80-9
MW:	405.89 D

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JZP-361

Item number: TGM-T27703-100mg

Description: JZP-361 is a specific MAGL inhibitor with IC50s of 46 nM, 7.24 µM, and 1.79 µM for human recombinant MAGL, human recombinant FAAH, and human hABHD6. JZP-361 displays anti-histaminergic activities. JZP-361 can be used in studies about asthma. Target: MAGL, Histamine Receptor, Lipase. Smiles:...

Keywords:	JZP361 , JZP 361
CAS	1680193-80-9
MW:	405.88 D

From 37.00€ *

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