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RX-518
Item number: Cay40922-10
RX-518 is an inhibitor of EGFR. It inhibits the growth of A431, H1975, and HCC827 cancer cells expressing wild-type EGFR, EGFR L858R/T790M, and EGFR del19, respectively (GI50s = 5, 10, and 689 nM, respectively).Formal Name:...
| Keywords: | CK-101, Olafertinib,... |
| Application: | EGFR inhibitor |
| CAS | 1660963-42-7 |
| MW: | 530.6 D |
From 132.00€
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Olafertinib
Item number: TGM-TQ0255-100mg
Description: Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC. Target: EGFR. Smiles: OCCN1CCN(CC1)c1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)c(F)c1F. References: Xiangping Qian, et al. Abstract 2078: CK-101 (RX518), a...
| Keywords: | RX-518, EGFR-IN-3, CK-101 |
| Application: | EGFR inhibitor |
| CAS | 1660963-42-7 |
| MW: | 530.57 D |
From 39.00€
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