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Item number: Cay37750-1

NIK SMI1 is an inhibitor of NF-kappaB-inducing kinase (NIK, Ki = 0.23 nM). It inhibits NF-kappaB activation in a reporter assay using HEK293 cells (IC50 = 34 nM). NIK SMI1 inhibits B cell activating factor-induced survival of isolated mouse splenic B cells (IC50 = 373 nM).Formal Name:...

Keywords:	6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxo-3-pyrrolidinyl]ethynyl]phenyl]-4-methoxy-2-pyridinecarboxamide
Application:	NIK inhibitor
CAS	1660114-31-7
MW:	365.4 D

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