2 products were found matching "1654725-02-6"!
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GLPG1837
Item number: TGM-T7083-100mg
Description: GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively. Target: Autophagy, CFTR. Smiles: CC1(C)Cc2c(sc(NC(=O)c3cc[nH]n3)c2C(N)=O)C(C)(C)O1. References: Van der Plas SE, et al. Discovery of...
| Keywords: | ABBV-974 |
| Application: | CFTR potentiator |
| CAS | 1654725-02-6 |
| MW: | 348.42 D |
From 31.00€
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GLPG1837
Item number: Cay9003143-1
GLPG1837 is a potentiator of cystic fibrosis transmembrane conductance regulator (CFTR). It increases forskolin-induced opening of wild-type and mutant CFTRs expressing the F508 deletion (F508del) and G551D missense mutations with EC50 values of 88, 3, and 339 nM, respectively, in a reporter assay. GLPG1837...
| Keywords: | ABBV-974, N-[3-(aminocarbonyl)-4,7-dihydro-5,5,7,7-tetramethyl-5H-thieno[2,3-c]pyran-2-yl]-1H-pyrazole-3-carboxamide |
| Application: | CFTR potentiator |
| CAS | 1654725-02-6 |
| MW: | 348.4 D |
From 61.00€
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