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Item number: Cay30376-5

ITI214 is an inhibitor of phosphodiesterase 1 (PDE1, Ki = 0.058 nM). It is selective for PDE1 over PDE2A, -3B, -4A, -5A, -6, -7B, -8A, -9A, -10A, and -11A (Kis = 0.16-18 µM). ITI214 (3 and 6 mg/kg) enhances novel object recognition in rats. It increases prefrontal cortex cAMP and cGMP levels in mice when...

Keywords:	(6aR,9aS)-2-[[4-(6-fluoro-2-pyridinyl)phenyl]methyl]-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-cyclopent[4,5]imidaz...
Application:	PDE1 inhibitor
CAS	1642303-38-5
MW:	605.6 D

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ITI-214

Item number: TGM-T11689-100mg

Description: ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). Target: PDE. Smiles:...

Keywords:	ITI214
CAS	1642303-38-5
MW:	605.56 D

From 65.00€ *

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