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FIIN-3
Item number: Cay20709-1
FIIN-3 is an inhibitor of FGF receptors (FGFRs, IC50s = 13, 21, 31, and 35 nM for recombinant FGFR1-4, respectively). It is selective for FGFRs over a panel of 456 kinases at a concentration of 1 µM, however, it does inhibit EGFR (IC50 = 204 nM). FIIN-3 inhibits growth of Ba/F3 cells that are dependent on the kinase...
| Keywords: | N-[4-[[[[(2,6-dichloro-3,5-dimethoxyphenyl)amino]carbonyl][6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino... |
| Application: | Potent, selective, irreversible, covalent FGFR inhibitor |
| CAS | 1637735-84-2 |
| MW: | 691.6 D |
From 56.00€
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FIIN-3
Item number: TGM-T3466-100mg
Description: FIIN-3, an irreversible inhibitor of FGFR (Fibroblast Growth Factor Receptor), is a chemical compound designed to bind permanently to FGFR, thereby inhibiting its activity and potential downstream signaling pathways. Target: FGFR, EGFR. Smiles:...
| Application: | Potent, selective, irreversible, covalent FGFR inhibitor |
| CAS | 1637735-84-2 |
| MW: | 691.61 D |
From 32.00€
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