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YM-90709
Item number: TGM-T3133-100mg
Description: YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor. Target: IL Receptor, Interleukin. Smiles: COc1cc2CC(C)(C)n3c(cc4nc5ccccc5nc34)-c2cc1OC. References: Morokata T, et al. Int Immunopharmacol. 2004 Jul,4(7):873-83.
| Keywords: | YM90709, YM 90709 |
| Application: | Interleukin 5 (IL-5) receptor competitive antagonist |
| CAS | 163769-88-8 |
| MW: | 359.42 D |
From 31.00€
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YM-90709
Item number: Cay23448-5
YM-90709 is a competitive antagonist of the interleukin-5 (IL-5) receptor that has IC50 values of 1 and 0.57 µM for peripheral human eosinophils and eosinophilic HL-60 clone 15 cells, respectively, in a radioligand binding assay. It inhibits IL-5-induced eosinophil survival (IC50 = 0.45 µM) and JAK2 phosphorylation...
| Keywords: | 5,6-dihydro-2,3-dimethoxy-6,6-dimethyl-benz[7,8]indolizino[2,3-b]quinoxaline |
| Application: | Interleukin 5 (IL-5) receptor competitive antagonist |
| CAS | 163769-88-8 |
| MW: | 359.4 D |
From 128.00€
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