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hVEGF-IN-1
Item number: TGM-T4288-100mg
Description: hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity. Target: VEGFR. Smiles: CCN(CC)CCOc1ccc(Nc2nc(nc3ccccc23)-c2ccccc2NC(=O)CCN2CCN(C)CC2)cc1. References: Discovery of Small Molecules for Repressing Cap-Independent Translation of Human VascularEndothelial Growth Factor (hVEGF) as...
| Application: | VEGFA translation inhibitor |
| CAS | 1637443-98-1 |
| MW: | 581.75 D |
From 58.00€
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hVEGF-IN-1
Item number: Cay37550-1
hVEGF-IN-1 is an inhibitor of VEGFA translation. It binds to the mRNA encoding VEGF-A (Kd = 4.64 µM) and decreases its translation when used at a concentration of 1.5 µM. hVEGF-IN-1 (3 µM) reduces migration of MCF-7 breast cancer cells. It decreases tumor growth and weight without reducing body weight in an MCF-7...
| Keywords: | Human Vascular Endothelial Growth Factor Inhibitor 1,... |
| Application: | VEGFA translation inhibitor |
| CAS | 1637443-98-1 |
| MW: | 581.8 D |
From 107.00€
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