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AF64394
Item number: TGM-T8407-100mg
Description: AF64394 is a selective inverse agonist of GPR3(pIC50 : 7.3). Target: GPR. Smiles: CC(C)Oc1cc(Cl)ccc1CNc1cc(nc2ncnn12)-c1ccccc1. References: Jensen T, et al. The identification of GPR3 inverse agonist AF64394, the first small molecule inhibitor of GPR3 receptor function. Bioorg Med Chem Lett. 2014 Nov...
| Application: | GPR3 inverse agonist |
| CAS | 1637300-25-4 |
| MW: | 393.87 D |
From 34.00€
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AF64394
Item number: Cay36826-10
AF64394 is an inverse agonist of the orphan G protein-coupled receptor GPR3. It selectively inhibits cAMP accumulation in HEK293 cells expressing GPR3 over GPR6 or GPR12 (IC50s = 0.5, 7.9, and 12 µM, respectively).Formal Name:...
| Keywords: | N-[[4-chloro-2-(1-methylethoxy)phenyl]methyl]-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine |
| Application: | GPR3 inverse agonist |
| CAS | 1637300-25-4 |
| MW: | 393.9 D |
From 77.00€
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