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680C91
680C91

Item number: Cay34823-10

680C91 is an inhibitor of tryptophan 2,3-dioxygenase (TDO, IC50s = 1.46 and 0.28 µM for the mouse and human enzymes, respectively). It is selective for TDO over indoleamine 2,3-dioxygenase (IDO, IC50 = >80 µM for the mouse enzyme). 680C91 (40 µM) inhibits the migration of SK-MEL-28 melanoma cells induced by...
Keywords: 6-fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole
Application: TDO inhibitor
CAS 163239-22-3
MW: 238.3 D
From 92.00€ *
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680C91
680C91

Item number: TGM-T22251-100mg

Description: 680C91 is a potent and selective inhibitor of TDO, and its Ki is 51 nM. Target: Others. Smiles: Fc1ccc2c(\C=C\c3cccnc3)c[nH]c2c1. References: M Salter, et al. Biochem Pharmacol. 1995 May 17,49(10):1435-42.
Application: TDO inhibitor
CAS 163239-22-3
MW: 238.26 D
From 40.00€ *
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