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Inecalcitol
Item number: Cay37288-1
Inecalcitol is a derivative of calcitriol (Cay-71820) and an agonist of the vitamin D receptor (VDR). It induces reporter gene expression in VDR-expressing COS-1 cells when used at a concentration of 1 nM. Inecalcitol induces differentiation of HL-60 leukemia and MG-63 osteosarcoma cells (EC50s = 6.2 and 0.18 nM,...
| Keywords: | 19-nor-14-epi-23-yne-1,25-dihydroxy Vitamin D3, TX 522,... |
| Application: | Vitamin D receptor agonist |
| CAS | 163217-09-2 |
| MW: | 400.6 D |
From 40.00€
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Inecalcitol
Item number: TGM-T24166-10mg
Description: Inecalcitol (TX 522) is the growth inhibitor of human breast cancer cells. Inecalcitol is a unique vitamin D3 analog with Kd of 0.53 nM. Target: Apoptosis. Smiles: [H][C@]12CC[C@H]([C@H](C)CC#CC(C)(C)O)[C@@]1(C)CCC\C2=C/C=C1C[C@@H](O)C[C@H](O)C1. References: Ryoko Okamoto, et al. Inecalcitol, an analog...
| Keywords: | TX-522, TX 522, TX522 |
| CAS | 163217-09-2 |
| MW: | 400.59 D |
From 45.00€
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