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GSK3008348
Item number: Cay43471-1
GSK3008348 is an integrin alphaVbeta6 inhibitor (Ki = 0.01 nM). It is selective for integrin alphaVbeta6 over integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, and alphaVbeta8 (IC50s = 3.9, 50, 1,000, 126, and 16 nM, respectively, in cell adhesion assays). GSK3008348 induces internalization and degradation of...
| Keywords: | (betaS,3R)-beta-[3-(3,5-dimethyl-(1H-pyrazol-1-(yl)phenyl]-3-([2-(5,6,7,8-(tetrahydro-(1,8-(naphthyridin-(2-yl)ethyl]-1-py... |
| Application: | Integrin alphaVbeta6 inhibitor |
| CAS | 1629249-33-7 |
| MW: | 487.65 D |
From 53.00€
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GSK-3008348
Item number: TGM-T24108-25mg
Description: GSK-3008348 is an antagonist of integrin alpha(v)beta6. Target: Others. Smiles: CC=1N(C2=CC([C@@H](CN3C[C@H](CCC=4NC=5C(=CC4)CCCN5)CC3)CC(O)=O)=CC=C2)N=C(C)C1
| CAS | 1629249-33-7 |
| MW: | 487.64 D |
375.00€
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