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Item number: TGM-T15278-100mg

Description: Fezolinetant (ESN-364) is an antagonist of the neurokinin 3 receptor (NK3R). It is used for the treatment of menopausal hot flushes. Target: Neurokinin receptor. Smiles: C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1. References: Fraser GL, et al. The NK3 Receptor Antagonist ESN364 Interrupts Pulsatile...

Keywords:	ESN-364
Application:	Targets tachykinin receptor 3 (TACR3)
CAS	1629229-37-3
MW:	358.39 D

From 72.00€ *

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Fezolinetant

Item number: Cay39523-10

Fezolinetant is a neurokinin-3 (NK3) receptor antagonist (IC50 = 20 nM). It decreases plasma levels of luteinizing hormone (LH) in castrated cynomolgus monkeys when administered at a dose of 5 mg/kg. Fezolinetant (10 mg/kg) prevents increases in body weight and food intake but does not affect uterine weight or...

Keywords:	AS 3472693-00, ESN364,...
Application:	NK3 receptor antagonist
CAS	1629229-37-3
MW:	358.4 D

From 138.00€ *

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