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Item number: TGM-T5484-100mg

Description: GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM). Target: Histone Methyltransferase, Histone Demethylase. Smiles: O=c1[nH]c(Oc2cnn(Cc3ccccc3)c2)nc2cnccc12. References: Johansson C, et al. Structural analysis of human KDM5B guides histone demethylase inhibitor development. Nat...

CAS	1628332-52-4
MW:	319.32 D

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GSK467

Item number: Cay42103-1

A JARID1B inhibitor (IC50 = 0.02-0.1 µM), selective for JARID1B over KMD2, -3, -4, and -5 (IC50s = 1-10 µM). Formulation: A solid. InChI: InChI=1S/C17H13N5O2/c23-16-14-6-7-18-9-15(14)20-17(21-16)24-13-8-19-22(11-13)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H,20,21,23). InChIKey: ZTYRLXUTLYBVHH-UHFFFAOYSA-N. SMILES:...

Keywords:	2-[[1-(phenylmethyl)-1H-pyrazol-4-yl]oxy]- pyrido[3,4-d]pyrimidin-4(3H)-one
Application:	JARID1B (KDM5B) inhibitor
CAS	1628332-52-4
MW:	319.3 D

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