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Item number: TGM-T6877-100mg

Description: LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM). Target: S6 Kinase, Apoptosis. Smiles: CN1CCN(CC1)c1ccc(cc1)-c1ccncc1-c1cc(F)c(O)c(F)c1. References: Aronchik I, et al. Mol Cancer Res. 2014, 12(5), 803-812.

Application:	RSK inhibitor
CAS	1627710-50-2
MW:	381.42 D

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LJH685

Item number: Cay19913-10

LJH685 is an inhibitor of p90 ribosomal S6 kinases (RSKs, also known as MAP kinase-activated protein kinases, or MAPKAPKs) that inhibits RSK1, 2, and 3 in vitro with IC50 values of 6, 5, and 4 nM, respectively. It is selective for RSKs over a panel of 96 other kinases. LJH685 blocks RSK activity in cells, preventing...

Keywords:	2,6-difluoro-4-[4-[4-(4-methyl-1-piperazinyl)phenyl]-3-pyridinyl]-phenol
Application:	RSK inhibitor
CAS	1627710-50-2
MW:	381.4 D

From 44.00€ *

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