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Item number: Cay35279-10

PSB-CB5 is an antagonist of G protein-coupled receptor GPR18 (IC50 = 0.279 µM). It is 36-, 36-, and 14-fold selective for GPR18 over GPR55, cannabinoid 1 (CB1), and CB2 receptors, respectively. PSB-CB5 (1 µM) inhibits acrosomal exocytosis induced by the endogenous GPR18 ligand arachidonoyl glycine (NAGly, Cay-90051)...

Keywords:	CID-85469571, (2Z)-2-[[3-[(4-chlorophenyl)methoxy]phenyl]methylene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3(2H)-one
Application:	GPR18 antagonist
CAS	1627710-30-8
MW:	384.9 D

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PSB-CB5

Item number: TGM-T27019-10mg

Description: PSB-CB5 (GPR18-IN-32)2 is a GRP18 antagonist with anti-inflammatory activity and can be used to study obesity and metabolic disorders. Target: GPR. Smiles: O=C\1N2C(=N/C1=C\C3=CC(OCC4=CC=C(Cl)C=C4)=CC=C3)SCCC2. References: Kotanska M, et al. Effects of GPR18 Ligands on Body Weight and Metabolic...

Keywords:	CID-85469571, GPR18-IN-32
CAS	1627710-30-8
MW:	384.88 D

From 76.00€ *

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